Title : [Urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) and its isoenzyme B as a marker of the nephrotoxicity of gentamicin: re-test from an animal model].

Pub. Date : 1988 Mar

PMID : 3283687






4 Functional Relationships(s)
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1 [Urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) and its isoenzyme B as a marker of the nephrotoxicity of gentamicin: re-test from an animal model]. Gentamicins N-acetyl-alpha-glucosaminidase Homo sapiens
2 The urinary excretion of NAG following gentamicin treatment was studied in rabbit. Gentamicins N-acetyl-alpha-glucosaminidase Homo sapiens
3 Surprisingly, the high level of NAG excretion following the administration of gentamicin at 50 mg/kg/j is not accompanied by a marked excretion of isoenzyme B. Gentamicins N-acetyl-alpha-glucosaminidase Homo sapiens
4 These data indicate that increases in urinary NAG and isoenzyme B excretion following gentamicin treatment in Human are not always reliable indicators of renal tubular cell lysis. Gentamicins N-acetyl-alpha-glucosaminidase Homo sapiens