Title : Heparin Anti-Xa Activity, a Readily Available Unique Test to Quantify Apixaban, Rivaroxaban, Fondaparinux, and Danaparoid Levels.

Pub. Date : 2021 Mar 1

PMID : 32833716






3 Functional Relationships(s)
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1 METHODS: In the derivation cohort then in the validation cohort, via receiver operatingcharacteristics (ROC) curve analysis, we evaluated the ability of heparin anti-Xaassay to detect levels of factor-Xa inhibitors above or below the abovementioned safety thresholds recommended for an invasive procedure (screening test). Heparin coagulation factor X Homo sapiens
2 In a validation cohort, the estimated level of each factor-Xa inhibitor was thus inferred from heparin anti-Xa activity. Heparin coagulation factor X Homo sapiens
3 RESULTS: Among 989 (355 patients) and 756 blood samples (420 patients) in the derivation and validation cohort, there was a strong linear relationship between heparin anti-Xa activities and factor-Xa inhibitors measured level (r = 0.99 [95% confidence interval {CI}, 0.99-0.99]). Heparin coagulation factor X Homo sapiens