Title : The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.

Pub. Date : 2020 Oct 1

PMID : 32830871






1 Functional Relationships(s)
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1 Collectively, arginine-rich DPR-mediated impairment of EXOSC10 and the RNA exosome complex compromises repeat RNA metabolism and may thus exacerbate C9orf72-FTLD/ALS pathologies in a vicious cycle. Arginine C9orf72-SMCR8 complex subunit Homo sapiens