Title : Ranolazine protects against diabetic cardiomyopathy by activating the NOTCH1/NRG1 pathway.

Pub. Date : 2020 Nov 15

PMID : 32828943






2 Functional Relationships(s)
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1 NOTCH1 inhibitor (DAPT) was used to explore the mechanism of ranolazine. dapt notch receptor 1 Rattus norvegicus
2 Ranolazine-induced NOTCH1 activated NRG1 and inhibited the downstream apoptosis-related pathway, while DAPT partially inhibited ranolazine-induced NOTCH1 and NRG1 expression. dapt notch receptor 1 Rattus norvegicus