Title : Merged Tacrine-Based, Multitarget-Directed Acetylcholinesterase Inhibitors 2015-Present: Synthesis and Biological Activity.

Pub. Date : 2020 Aug 19

PMID : 32825138






1 Functional Relationships(s)
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1 Acetylcholinesterase is an important biochemical enzyme in that it controls acetylcholine-mediated neuronal transmission in the central nervous system, contains a unique structure with two binding sites connected by a gorge region, and it has historically been the main pharmacological target for treatment of Alzheimer"s disease. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens