Title : Structural elucidation of the cis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation.

Pub. Date : 2020 Aug 25

PMID : 32817466






1 Functional Relationships(s)
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Protein Name
Organism
1 Comparison of NgBR/DHDDS with homodimeric cis-PTase structures leads to a model where the elongating isoprene chain extends beyond the enzyme"s active site tunnel, and an insert within the alpha3 helix helps to stabilize this energetically unfavorable state to enable long-chain synthesis to occur. isoprene NUS1 dehydrodolichyl diphosphate synthase subunit Homo sapiens