Title : The redox function of apurinic/apyrimidinic endonuclease 1 as key modulator in photodynamic therapy.

Pub. Date : 2020 Oct

PMID : 32805556






1 Functional Relationships(s)
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1 The APE1"s downregulation correlated to an increase of DNA fragmentation (17% and 66% in A549 and HeLa cells, respectively) and cell death rate (total: 24% and 74% in A549 and HeLa cells, respectively) characterized by annexin V and 7-AAD markers as well as a considerable difference in superoxide detected in mitochondria (29% and 78% in A549 and HeLa cells, respectively). 7-aminoactinomycin D apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens