Title : Significance of SGLT2 inhibitors: lessons from renal clinical outcomes in patients with type 2 diabetes and basic researches.

Pub. Date : 2020 Jul

PMID : 32802705






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The proposed mechanisms for the renoprotective effects of SGLT2 inhibitors include the action of tubulo-glomerular feedback system and attenuation of hypoxia and metabolic stress in proximal tubular cells mediated through the inhibition of excessive glucose and sodium reabsorption, increased erythropoiesis, or increased ketone body production. Ketones solute carrier family 5 member 2 Homo sapiens