Pub. Date : 2020
PMID : 32802178
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mechanistic studies revealed that arsenic plus BaP co-exposure up-regulates MCL-1 protein levels by synergistically activating the PI3K/Akt/mTOR pathway to increase the level of a deubiquitinase USP7, which in turn reduces the level of MCL-1 protein ubiquitination and prevents its subsequent proteasome degradation. | Benzo(a)pyrene | AKT serine/threonine kinase 1 | Homo sapiens |