Title : F-box protein FBXO31 modulates apoptosis and epithelial-mesenchymal transition of cervical cancer via inactivation of the PI3K/AKT-mediated MDM2/p53 axis.

Pub. Date : 2020 Oct 15

PMID : 32800832






1 Functional Relationships(s)
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Protein Name
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1 Overexpression of MDM2 ameliorated the inhibitory effect of FBXO31 on SiHa cells, while the MDM2/p53 axis-specific inhibitor Nutlin-3a facilitated this inhibitory effect. nutlin 3 tumor protein p53 Homo sapiens