Title : Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism.

Pub. Date : 2020 Aug 11

PMID : 32796716






1 Functional Relationships(s)
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1 Its decreased expression plays a prominent role in the heart, liver and brain of rat as manifestations of fetal programming produced by deficit in vitamin B12 and folate during pregnancy and lactation through imbalanced methylation/acetylation of PGC1alpha and altered expression and methylation of nuclear receptors. Folic Acid PPARG coactivator 1 alpha Rattus norvegicus