Title : MicroRNA-212-3p inhibits paclitaxel resistance through regulating epithelial-mesenchymal transition, migration and invasion by targeting ZEB2 in human hepatocellular carcinoma.

Pub. Date : 2020 Oct

PMID : 32774496






4 Functional Relationships(s)
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1 Moreover, miR-212-3p was reduced and its overexpression resulted in decreased cell viability, half maximal inhibitory concentration (IC50) of PTX and levels of P-glycoprotein and glutathione S-transferase pi, but increased cell apoptosis, in Huh7/PTX cells. mir-212-3p MIR7-3 host gene Homo sapiens
2 However, miR-212-3p knockdown induced opposite effects in Huh7 cells. mir-212-3p MIR7-3 host gene Homo sapiens
3 Furthermore, EMT, migration and invasion were induced in Huh7/PTX cells and the addition of miR-212-3p inhibited EMT, migration and invasion. mir-212-3p MIR7-3 host gene Homo sapiens
4 Meanwhile, miR-212-3p abrogation caused the opposite effects in Huh7 cells. mir-212-3p MIR7-3 host gene Homo sapiens