Pub. Date : 2020 Oct 1
PMID : 32771556
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 3beta-Hydroxycholest-5-en-7-one from seahorse alleviates lipopolysaccharide-induced inflammatory responses by downregulating miR-98-5p. | 7-ketocholesterol | microRNA 98 | Mus musculus |
| 2 | Our results demonstrated that 3beta-hydroxycholest-5-en-7-one exerted an anti-inflammatory effect via miR-98-5p, which negatively regulated the expression of its target gene TNFAIP3. | 7-ketocholesterol | microRNA 98 | Mus musculus |
| 3 | SIGNIFICANCE: 3beta-Hydroxycholest-5-en-7-one alleviates inflammation by downregulating miR-98-5p and upregulating TNFAIP3, thereby blocking NF-kappaB pathway activation. | 7-ketocholesterol | microRNA 98 | Mus musculus |