Pub. Date : 2022 Feb
PMID : 32762281
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Treatment of PI3K inhibitor LY294002 significantly increased the apoptosis rate of HBMVECs, and this effect was significantly reversed by transfection of miR-17-5p mimics, while further dramatically enhanced by overexpression of PTEN.Conclusion: MiR-17-5p could amelioratecerebral I/R injury-induced cell apoptosis by directly targeting PTEN and regulation of PI3K/AKT/mTOR signaling. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | AKT serine/threonine kinase 1 | Homo sapiens |