Pub. Date : 2020 Oct
PMID : 32757222
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, the high level of CORT induced by PCE downregulated the H3K9ac and expression levels of 11beta-HSD2 through promoting glucocorticoid receptor (GR) into the nucleus of bone marrow mesenchymal stem cells (BMSCs) and recruiting histone deacetylase 11 (HDAC11) binding to 11beta-HSD2 promoter region, which further enhanced the effect of CORT on suppressing osteogenic function of BMSCs. | Corticosterone | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |
| 2 | Moreover, the high level of CORT induced by PCE downregulated the H3K9ac and expression levels of 11beta-HSD2 through promoting glucocorticoid receptor (GR) into the nucleus of bone marrow mesenchymal stem cells (BMSCs) and recruiting histone deacetylase 11 (HDAC11) binding to 11beta-HSD2 promoter region, which further enhanced the effect of CORT on suppressing osteogenic function of BMSCs. | Corticosterone | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |
| 3 | Moreover, the high level of CORT induced by PCE downregulated the H3K9ac and expression levels of 11beta-HSD2 through promoting glucocorticoid receptor (GR) into the nucleus of bone marrow mesenchymal stem cells (BMSCs) and recruiting histone deacetylase 11 (HDAC11) binding to 11beta-HSD2 promoter region, which further enhanced the effect of CORT on suppressing osteogenic function of BMSCs. | Corticosterone | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |