Pub. Date : 2020 Aug
PMID : 32742376
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In HCT116 cells expressing wild-type (wt) TP53, SIRT inhibitors were found to act antagonistically with multiple chemotherapeutic agents (cisplatin, 5-fluorouracil, oxaliplatin, gefitinib, LY294002 and metformin), and decreased the anti-tumor effects of these agents. | Metformin | tumor protein p53 | Homo sapiens |