Title : M2-Like Tumor-Associated Macrophage-Targeted Codelivery of STAT6 Inhibitor and IKKβ siRNA Induces M2-to-M1 Repolarization for Cancer Immunotherapy with Low Immune Side Effects.

Pub. Date : 2020 Jul 22

PMID : 32724855






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The smart nanodrug effectively functions M2-to-M1 repolarization via M2-targeted codelivery of IKKbeta siRNA and STAT6 inhibitor AS1517499 (AS), which suppresses the tumor growth and metastasis. 4-(benzylamino)-2-((2-(3-chloro-4-hydroxyphenyl)ethyl)amino)pyrimidine-5-carboxamide signal transducer and activator of transcription 6 Homo sapiens