Title : Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells.

Pub. Date : 2020 Jul 24

PMID : 32722075






1 Functional Relationships(s)
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1 In addition, LY and TAM combination induced the apoptotic genes Caspase-3, Caspase-7, and p53, as well as p21 as cell cycle promotor, and significantly downregulated the anti-apoptotic genes Bcl-2 and survivin. Tamoxifen tumor protein p53 Homo sapiens