Title : The ups and downs of Poly(ADP-ribose) Polymerase-1 inhibitors in cancer therapy-Current progress and future direction.

Pub. Date : 2020 Oct 1

PMID : 32717529






1 Functional Relationships(s)
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1 To date, four PARP1 inhibitors namely olaparib, rucaparib, niraparib and talazoparib, have been approved by Food and Drug Administration (FDA) for treating ovarian cancer and breast cancer with BRCA1/2 mutation. talazoparib BRCA1 DNA repair associated Homo sapiens