Title : Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition.

Pub. Date : 2020 Jul 19

PMID : 32707731






1 Functional Relationships(s)
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1 Here, we showed that Cbl dampened NLRP3 inflammasome activation by inhibiting glycolysis, as demonstrated with Cbl knockout cells and treatment with the Cbl inhibitor hydrocotarnine. hydrocotarnine NLR family pyrin domain containing 3 Homo sapiens