Pub. Date : 2020 Jul 14
PMID : 32699853
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro, binding of ACE2 and heparin to spike protein ectodomains occurs independently and a ternary complex can be generated using heparin as a template. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | In vitro, binding of ACE2 and heparin to spike protein ectodomains occurs independently and a ternary complex can be generated using heparin as a template. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 3 | Unfractionated heparin, non-anticoagulant heparin, treatment with heparin lyases, and purified lung heparan sulfate potently block spike protein binding and infection by spike protein-pseudotyped virus and SARS-CoV-2 virus. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 4 | Unfractionated heparin, non-anticoagulant heparin, treatment with heparin lyases, and purified lung heparan sulfate potently block spike protein binding and infection by spike protein-pseudotyped virus and SARS-CoV-2 virus. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 5 | Unfractionated heparin, non-anticoagulant heparin, treatment with heparin lyases, and purified lung heparan sulfate potently block spike protein binding and infection by spike protein-pseudotyped virus and SARS-CoV-2 virus. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 6 | Unfractionated heparin, non-anticoagulant heparin, treatment with heparin lyases, and purified lung heparan sulfate potently block spike protein binding and infection by spike protein-pseudotyped virus and SARS-CoV-2 virus. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 7 | Unfractionated heparin, non-anticoagulant heparin, treatment with heparin lyases, and purified lung heparan sulfate potently block spike protein binding and infection by spike protein-pseudotyped virus and SARS-CoV-2 virus. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 8 | Unfractionated heparin, non-anticoagulant heparin, treatment with heparin lyases, and purified lung heparan sulfate potently block spike protein binding and infection by spike protein-pseudotyped virus and SARS-CoV-2 virus. | Heparin | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |