Title : Antimalarial-agent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV-2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19.

Pub. Date : 2021 Oct

PMID : 32696720






2 Functional Relationships(s)
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1 In this paper, we demonstrate how hydroxychloroquine can act as a good inhibitor of SARS-CoV-2 Spike protein receptor-binding-domain using molecular docking studies. Hydroxychloroquine surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 We also unveil how hydroxychloroquine can interfere in the prevention of Lys353 in hACE2 from interacting with the corresponding binding hotspot present on the Spike protein. Hydroxychloroquine surface glycoprotein Severe acute respiratory syndrome coronavirus 2