Title : Colchicine mesoporous silica nanoparticles/hydrogel composite loaded cotton patches as a new encapsulator system for transdermal osteoarthritis management.

Pub. Date : 2020 Dec 1

PMID : 32693125






1 Functional Relationships(s)
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1 The therapeutic investigation of colchicine formulated patches in mono-iodoacetate (MIA)-induced rat osteoarthritis model depicted improved locomotor activity, glutathione blood level, and remarkable decline in levels of malondialdehyde, nitric oxide, TNF-alpha, and COX-2. Colchicine cytochrome c oxidase II, mitochondrial Rattus norvegicus