Pub. Date : 2020 Oct
PMID : 32691726
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MATERIALS AND METHODS: The enzymatic activity of several CYP2D6 genetic variants; i.e., CYP2D6.1 (wild type), CYP2D6.2, CYP2D6.10, and CYP2D6.39, was assessed by examining the O-demethylation of dextromethorphan. | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | RESULTS AND CONCLUSION: The intrinsic clearance of dextromethorphan (Vmax/Km) for CYP2D6.2, CYP2D6.10, and CYP2D6.39 were 0.565-, 0.0376-, and 0.470-fold of that for wild type, respectively. | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 3 | RESULTS AND CONCLUSION: The intrinsic clearance of dextromethorphan (Vmax/Km) for CYP2D6.2, CYP2D6.10, and CYP2D6.39 were 0.565-, 0.0376-, and 0.470-fold of that for wild type, respectively. | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 4 | RESULTS AND CONCLUSION: The intrinsic clearance of dextromethorphan (Vmax/Km) for CYP2D6.2, CYP2D6.10, and CYP2D6.39 were 0.565-, 0.0376-, and 0.470-fold of that for wild type, respectively. | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |