Pub. Date : 2020 Jan-Dec
PMID : 32686984
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study is to explore the effects of RAPA combined with CDDP on the expression of TNF-alpha in osteosarcoma MG-63 cells. | Cisplatin | tumor necrosis factor | Homo sapiens |
| 2 | The results of PCR showed that both the separate drug use and drug combination could significantly lower the relative expression quantity of TNF-alpha gene (*P < 0.5), but the combination was more effective (*P < 0.5); the expression quantity of TNF-alpha gene in the RAPA + CDDP group at 48 h was much lower than that at 24 h (***P < 0.001). | Cisplatin | tumor necrosis factor | Homo sapiens |
| 3 | The results of PCR showed that both the separate drug use and drug combination could significantly lower the relative expression quantity of TNF-alpha gene (*P < 0.5), but the combination was more effective (*P < 0.5); the expression quantity of TNF-alpha gene in the RAPA + CDDP group at 48 h was much lower than that at 24 h (***P < 0.001). | Cisplatin | tumor necrosis factor | Homo sapiens |
| 4 | RAPA combined with CDDP can significantly reduce the expression of TNF-alpha in MG-63 cells, which is time dependent. | Cisplatin | tumor necrosis factor | Homo sapiens |