Title : Putative Genes and Pathways Involved in the Acne Treatment of Isotretinoin via Microarray Data Analyses.

Pub. Date : 2020

PMID : 32685503






1 Functional Relationships(s)
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1 Using isotretinoin for 1 week, LCN2, PTGES, and GDF15 were upregulated and might mediate sebocytes apoptosis and thus decreased sebum production; CCL2 originated from activated TNF signaling pathway and S100A7 could be related with "acne-flare". Isotretinoin tumor necrosis factor Homo sapiens