Title : NPC1L1 and ABCG5/8 induction explain synergistic fecal cholesterol excretion in ob/ob mice co-treated with PPAR-α and LXR agonists.

Pub. Date : 2020 Oct

PMID : 32661772






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Synergistic efficacy on fecal cholesterol excretion following co-treatment with PPAR-alpha and LXR agonists occurred through a combination of RCT, TICE, and the key enzyme in bile synthesis, cholesterol 7-alpha hydroxylase (cyp7a1). Cholesterol cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus
2 Synergistic efficacy on fecal cholesterol excretion following co-treatment with PPAR-alpha and LXR agonists occurred through a combination of RCT, TICE, and the key enzyme in bile synthesis, cholesterol 7-alpha hydroxylase (cyp7a1). Cholesterol cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus