Title : Potent Cytolytic Activity and Specific IL15 Delivery in a Second-Generation Trispecific Killer Engager.

Pub. Date : 2020 Sep

PMID : 32661096






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 A CD33-targeting second-generation TriKE induced stronger and more specific NK cell proliferation without T-cell stimulation, enhanced in vitro NK cell activation and killing of CD33-expressing targets, and improved tumor control in preclinical mouse models. trike CD33 antigen Mus musculus
2 A CD33-targeting second-generation TriKE induced stronger and more specific NK cell proliferation without T-cell stimulation, enhanced in vitro NK cell activation and killing of CD33-expressing targets, and improved tumor control in preclinical mouse models. trike CD33 antigen Mus musculus