Pub. Date : 2020 Nov
PMID : 32660223
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Repeated Administration of Baclofen Modulates TRPV-1 Channel Expression by PKC Pathway in Dorsal Root Ganglia of Spinal Cord in Morphine Tolerance Model of Rats. | Morphine | protein kinase C, gamma | Rattus norvegicus |
| 2 | In morphine tolerance group, both TRPV-1/PKC gene expression and protein levels increased in comparison with the control group. | Morphine | protein kinase C, gamma | Rattus norvegicus |
| 3 | Conclusion: Baclofen can enhance anti-nociceptive effect of morphine by modulating TRPV-1 channel and PKC activity. | Morphine | protein kinase C, gamma | Rattus norvegicus |