Title : Evaluation of the toxicity of the dopaminergic neurotoxins MPTP and MPP+ in PC12 pheochromocytoma cells: binding and biological studies.

Pub. Date : 1988 Dec 5

PMID : 3264604






1 Functional Relationships(s)
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1 Exposure of PC12 cells to 0.5 mM MPTP for 72 h resulted in a 50% cell loss with respect to the control cells, and clorgyline, a MAO-A inhibitor, antagonized this toxic effect. Clorgyline monoamine oxidase A Rattus norvegicus