Pub. Date : 2020 Sep
PMID : 32629108
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1. | 11-ketotestosterone | aldo-keto reductase family 1 member D1 | Homo sapiens |
| 2 | We show that inactivation of 11-ketotestosterone is predominantly driven by AKR1D1, which efficiently catalyses the 5beta-reduction of 11-ketotestosterone, committing it to a metabolic pathway that terminates in 11-ketoetiocholanolone. | 11-ketotestosterone | aldo-keto reductase family 1 member D1 | Homo sapiens |
| 3 | We show that inactivation of 11-ketotestosterone is predominantly driven by AKR1D1, which efficiently catalyses the 5beta-reduction of 11-ketotestosterone, committing it to a metabolic pathway that terminates in 11-ketoetiocholanolone. | 11-ketotestosterone | aldo-keto reductase family 1 member D1 | Homo sapiens |