Pub. Date : 2020 Oct
PMID : 32627280
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deoxyshikonin inhibits cisplatin resistance of non-small-cell lung cancer cells by repressing Akt-mediated ABCB1 expression and function. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Activation of protein kinase B (Akt) pathway attenuated the effect of deoxyshikonin on cisplatin resistance and ABCB1 expression and function in A549/cis and H1299/cis cells. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, deoxyshikonin suppressed cisplatin resistance in cisplatin-resistant NSCLC cells by repressing Akt signaling-mediated ABCB1 expression. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |