Title : Novel antibody-drug conjugates: current and future roles in gynecologic oncology.

Pub. Date : 2021 Feb 1

PMID : 32618744






1 Functional Relationships(s)
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1 In the last few years HER2/neu, folic acid-alpha (FRalpha) and Trop-2 overexpression have been exploited as excellent targets by novel ADCs such as Trastuzumab emtansine (T-DM1), SYD985, IMGN853 (Mirvetuximab soravtansine) and Sacituzumab govitecan (SG, IMMU-132) in multiple tumors including ovarian, endometrial and cervical cancers. Folic Acid rabaptin, RAB GTPase binding effector protein 2 Homo sapiens