Title : Plasma insulin-like growth factor binding protein 1 in pulmonary arterial hypertension.

Pub. Date : 2021 Feb

PMID : 32597241






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 IGFBP-1 correlated specifically to N-terminal prohormone of brain natriuretic peptide (NT-proBNP) (r = 0.44, p < .002), mean right atrial pressure (r = 0.41, p < .004), venous oxygen saturation (r = -0.43, p < .003), cardiac index (r = -0.32, p < .03) and 6-minute walking distance (r = -0.29, p < .05). nt-probnp insulin like growth factor binding protein 1 Homo sapiens
2 However, IGFBP-1 changes, between baseline and follow-up, correlated to changes in NT-proBNP (r = 0.48, p < .006). nt-probnp insulin like growth factor binding protein 1 Homo sapiens
3 Conclusion: Plasma IGFBP-1 levels at PAH diagnosis show moderate association to NT-proBNP and hemodynamics as well as with ESC/ERS and REVEAL risk scores. nt-probnp insulin like growth factor binding protein 1 Homo sapiens