Title : Enhancing fatty acid oxidation negatively regulates PPARs signaling in the heart.

Pub. Date : 2020 Sep

PMID : 32592696






3 Functional Relationships(s)
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1 ACC2 deletion had a significant impact on the global transcriptome including downregulation of the peroxisome proliferator-activated receptors (PPARs) signaling and fatty acid degradation pathways. Fatty Acids acetyl-Coenzyme A carboxylase beta Mus musculus
2 Increasing fatty acids by HFD feeding normalized expression of fatty acid degradation genes in ACC2 deficient mouse hearts to the same level as the control mice. Fatty Acids acetyl-Coenzyme A carboxylase beta Mus musculus
3 Increasing fatty acids by HFD feeding normalized expression of fatty acid degradation genes in ACC2 deficient mouse hearts to the same level as the control mice. Fatty Acids acetyl-Coenzyme A carboxylase beta Mus musculus