Title : Design, fabrication, and optimization of a dual function three-layer scaffold for controlled release of metformin hydrochloride to alleviate fibrosis and accelerate wound healing.

Pub. Date : 2020 Sep 1

PMID : 32590170






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Local administration of metformin-HCl substantially down-regulated the expression of fibrosis-involved genes: transforming growth factor (TGF-beta1), collagen type 1 (Col-I), fibronectin, collagen type 3 (Col-III), and alpha-smooth muscle actin (alpha-SMA). Metformin actin gamma 2, smooth muscle Rattus norvegicus