Pub. Date : 2020 Jun 25
PMID : 32587297
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The nucleoside analogs (DAC, 5AC and zebularine) were the most potent DHAs and increased the enzymatic activity of SIRT6 without showing any significant increase in other sirtuin isoforms. | Nucleosides | arylacetamide deacetylase | Homo sapiens |
| 2 | ChIP-Seq analysis of bone marrow cells derived from six acute myeloid leukemia (AML) patients and treated with the nucleoside analog DAC induced genome-wide acetylation changes in H3K9, the physiological substrate for SIRT6. | Nucleosides | arylacetamide deacetylase | Homo sapiens |