Title : Involvement of arachidonic acid cascade in working memory impairment induced by interleukin-1 beta.

Pub. Date : 2004 Jun

PMID : 32585792






1 Functional Relationships(s)
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1 Interleukin-1 beta, injected bilaterally into the dorsal hippocampus at a dose of 100 ng/side, significantly impaired working memory, and this impairment was attenuated by pretreatment with 10 mg/kg (s.c.) of diclofenac, a cyclooxygenase inhibitor. Diclofenac interleukin 1 beta Rattus norvegicus