Title : Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation.

Pub. Date : 2020 Jul 24

PMID : 32584575






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Analysis of IL-1beta and caspase-1 expression revealed that the new diterpenoids 15 and 18 are selective inhibitors of the NLRP3 inflammasome, reinforcing the previously demonstrated anti-inflammatory properties of hispanolone derivatives. hispanolone NLR family pyrin domain containing 3 Homo sapiens