Title : Attenuation of MPTP-induced dopaminergic neurotoxicity by a serotonin uptake blocker.

Pub. Date : 1988

PMID : 3258013






2 Functional Relationships(s)
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1 Monoamine oxidase-B (MAO-B) has been determined to be the enzyme responsible for the conversion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) into its toxic metabolite 1-methyl-4-phenylpyridine ion (MPP+). 1-Methyl-4-phenylpyridinium monoamine oxidase B Homo sapiens
2 Monoamine oxidase-B (MAO-B) has been determined to be the enzyme responsible for the conversion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) into its toxic metabolite 1-methyl-4-phenylpyridine ion (MPP+). 1-Methyl-4-phenylpyridinium monoamine oxidase B Homo sapiens