Pub. Date : 2020 Jun 3
PMID : 32572457
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Metformin, a commonly used oral antidiabetic drug, is known to elicit its action through 5" adenosine monophosphate-activated protein kinase (AMPK), a cellular metabolic regulator; however, its effect on Kir4.1 channels is unknown. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
2 | In rMC-1 cells, AMPK activation via AICAR and metformin resulted in increased Kir4.1 and intermediate core clock component Bmal-1 protein expression. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |