Pub. Date : 2020
PMID : 32566254
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibitors of Kdm6a and Kdm6b robustly abolished Zol-enhanced interleukin 1beta synthesis and secretion from macrophages. | Zoledronic Acid | KDM1 lysine (K)-specific demethylase 6B | Mus musculus |
| 2 | When Kdm6a and Kdm6b were pharmacologically inhibited in vivo, poor healing of the alveolar socket and inflammatory responses were ameliorated in Zol-treated mice. | Zoledronic Acid | KDM1 lysine (K)-specific demethylase 6B | Mus musculus |
| 3 | Taken together, we showed the pathologic role of Kdm6a and Kdm6b in Zol-promoted inflammatory responses and demonstrated that Kdm6a and Kdm6b are potential therapeutic targets for the treatment of BRONJ. | Zoledronic Acid | KDM1 lysine (K)-specific demethylase 6B | Mus musculus |
| 4 | Taken together, we showed the pathologic role of Kdm6a and Kdm6b in Zol-promoted inflammatory responses and demonstrated that Kdm6a and Kdm6b are potential therapeutic targets for the treatment of BRONJ. | Zoledronic Acid | KDM1 lysine (K)-specific demethylase 6B | Mus musculus |