Title : Does tamoxifen have a therapeutic role outside of breast cancer? A systematic review of the evidence.

Pub. Date : 2020 Jun

PMID : 32561074






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In vivo data consistently suggests that off target effects of tamoxifen are mediated through the ceramide pathway or through inhibition of protein kinase C (PKC). Tamoxifen proline rich transmembrane protein 2 Homo sapiens
2 In vivo data consistently suggests that off target effects of tamoxifen are mediated through the ceramide pathway or through inhibition of protein kinase C (PKC). Tamoxifen proline rich transmembrane protein 2 Homo sapiens
3 There is evidence to suggest that the ceramide or PKC pathway could act as a therapeutic target for tamoxifen or alternative chemotherapeutics and merits further investigation. Tamoxifen proline rich transmembrane protein 2 Homo sapiens