Title : Neuroprotective effect of Umbelliferone against Cerebral ischemia/Reperfusion induced neurological deficits: in-vivo and in-silico studies.

Pub. Date : 2021 Aug

PMID : 32552356






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1 Dose dependently treatment of umbelliferone down-regulated the neurological score, brain infarction, inflammatory mediator (TNF-alpha, IL-1beta, IL-6, COX-2, NF-kB and PGE2) in the serum and brain tissue as compared to I/R induced control group rats. 7-hydroxycoumarin cytochrome c oxidase II, mitochondrial Rattus norvegicus