Pub. Date : 2020 Jun 15
PMID : 32539736
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OXA administration upregulated p-CaMKKbeta, p-AMPK, and anti-inflammatory cytokines while downregulated p-NFkappaB and pro-inflammatory cytokines after ICH; this effect was reversed by STO-609 or JNJ-10397049 but not SB-334867. | 2-phenyloxazolone | calcium/calmodulin-dependent protein kinase kinase 2, beta | Mus musculus |
| 2 | CONCLUSIONS: OXA improved neurofunctional outcomes and mitigated brain edema after ICH, possibly through alleviating neuroinflammation via OXR2/CaMKKbeta/AMPK pathway. | 2-phenyloxazolone | calcium/calmodulin-dependent protein kinase kinase 2, beta | Mus musculus |