Title : Increased TLR4 pathway activation and cytokine imbalance led to lipopolysaccharide tolerance in monocytes from preeclamptic women.

Pub. Date : 2020 Jul

PMID : 32535227






1 Functional Relationships(s)
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1 The higher plasma levels of the TLR4 ligands hyaluronan, HMGB1 and hsp70, as well as the high concentration of TNF-alpha endogenously produced by monocytes, could induce the LPS tolerance phenomenon in these cells. Hyaluronic Acid toll like receptor 4 Homo sapiens