Title : Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy.

Pub. Date : 2020 Sep

PMID : 32526690






1 Functional Relationships(s)
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1 Curcumin inhibits levels of reactive oxygen species (ROS) and oxidative stress in hepatocytes by activating PPAR-alpha, and regulates upstream signaling pathways of autophagy AMPK and PI3K/AKT/mTOR, leading to an increase of the autophagic flow in hepatocytes. Curcumin AKT serine/threonine kinase 1 Homo sapiens