Title : Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.

Pub. Date : 2020 Aug 15

PMID : 32524997






2 Functional Relationships(s)
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1 Autophagy, negatively regulated by ERalpha, positively controls AIF-mediated apoptosis, as evidenced by the preventive effect of autophagy inhibitor 3-MA and siRNA targeting LC3, on the nuclear translocation of AIF and cell death induced by silibinin co-treatment with or without MPP. 3-methyladenine apoptosis inducing factor mitochondria associated 1 Homo sapiens
2 Autophagy, negatively regulated by ERalpha, positively controls AIF-mediated apoptosis, as evidenced by the preventive effect of autophagy inhibitor 3-MA and siRNA targeting LC3, on the nuclear translocation of AIF and cell death induced by silibinin co-treatment with or without MPP. 3-methyladenine apoptosis inducing factor mitochondria associated 1 Homo sapiens