Title : Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage.

Pub. Date : 2020 Aug 10

PMID : 32522601






2 Functional Relationships(s)
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1 Both 2% isoflurane and 3% sevoflurane significantly improved neurobehavioral function, and brain edema at 24 hours after SAH and attenuated cell death, associated with an increase in SphK1, a decrease in cleaved caspase-3 and COX2. Sevoflurane sphingosine kinase 1 Mus musculus
2 These findings suggest that both 2% isoflurane and 3% sevoflurane significantly inhibited EBI by suppressing post-SAH apoptosis and brain inflammation possibly via the SphK1-related pathway. Sevoflurane sphingosine kinase 1 Mus musculus