Pub. Date : 2020 Aug
PMID : 32512269
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ROS-dependent inhibition of the PI3K/Akt/mTOR signaling is required for Oroxylin A to exert anti-inflammatory activity in liver fibrosis. | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Here we further revealed that the inhibition of the PI3K/Akt/mTOR signaling was required for Oroxylin A to induce autophagy activation, which may be the underlying mechanism of the anti-inflammatory activity of Oroxylin A. | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Here we further revealed that the inhibition of the PI3K/Akt/mTOR signaling was required for Oroxylin A to induce autophagy activation, which may be the underlying mechanism of the anti-inflammatory activity of Oroxylin A. | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | thymoma viral proto-oncogene 1 | Mus musculus |
| 4 | Importantly, Oroxylin A inhibited PI3K/Akt/mTOR signaling by scavenging reactive oxygen species (ROS). | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | thymoma viral proto-oncogene 1 | Mus musculus |